权威例句
Effects of an Rb mutation in the mouse
Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis.
Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas
Cooperative tumorigenic effects of germline mutations in Rb and p53.
The E2F transcription factor is a cellular target for the RB protein
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107.
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
Dahlof B, Devereux RB, Kjeldsen SE, Julius S, Beevers G, de Faire U, et al., LIFE Study Group. Cardiovascular morbidity and mortalit...